The latest part of the study, which involved about 4,000 participants, also looked at the effect of replacing beta-carotene in the supplements formulation with lutein and zeaxanthin because of studies that found former smokers who take beta-carotene have a higher incidence of lung cancer. Researchers found a 20% improvement in progression to advanced AMD with the replacement, said Emily Chew, deputy director of epidemiology and clinical application for the National Eye Institute, a branch of the National Institutes of Health.
这项研究的最后一部分共涉及约4,000名参与者,它探讨了用叶黄素和玉米黄质来代替补充配方中β-胡萝卜素的影响,因为众多研究表明,曾经是烟民的人摄入β-胡萝卜素后,罹患肺癌的风险会更高。美国国家眼科研究所流行病学与临床应用部门副主任埃米莉•周(Emily Chew)说,研究人员发现,在服用替代营养素后,有20%的患者病变至年龄相关性黄斑变性晚期的过程有所改善。美国国家眼科研究所是美国国立卫生研究院的一个分支机构。
Dr. Chew said the AREDS study researchers recommend replacing the beta-carotene in supplements with lutein and zeaxanthin. Benefits from the supplements have been found only in people who are at high risk for advanced AMD or already have it in one eye.
周博士说,年龄相关性眼病研究的工作人员建议用叶黄素和玉米黄质来替代补充配方中的β-胡萝卜素。但该配方的益处仅仅只在那些晚期年龄相关性黄斑变性高发人群或者已有一只眼患上此疾的病人身上显现。
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