While these results are only preliminary, they do point to an entirely new way that doctors and patients might be able to tackle the growing obesity epidemic in the U.S. "This study suggests that the differences in the organisms may play at least some role in why people lose the weight they do, " says Dr. John DiBaise, a gastroenterologist at Mayo Clinic and one of study's authors. "Ultimately, we may not only be able to manipulate the microbes of obese individuals to look like those of normal weight people, but we might also potentially be able to predict a person's susceptibility to obesity."
虽然这些结论只是初级的,但它确实为医生和病人降低美国日益增长的肥胖症比率打开了一扇新的大门。作为这项研究的主要研究员,马奥诊所的胃肠病学家约翰.迪拜瑟医生说:“这项研究说明这些微生物肯定在在人们的减肥过程中扮演了什么角色。如果弄得好,我们可能不仅让胖子们的肠道菌群和正常人的一样,还可以预测一个人会不会变胖。”
What might be happening, suspects DiBaise, is that each person's ability to extract energy and store fat from food changes depending on which combination of bugs are living in the gut. Those who are morbidly obese, it seems, tend to nurture bugs that promote the fat storage process, which might be a factor in their excessive weight gain. The bypass patients appeared to follow a similar pattern but in the opposite direction, eating less first and then developing bugs appropriate to that diet. It's not clear how the physical act of reducing food intake drives that change, nor how long-lasting the possible slimming effects of the new bug population will be.
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