Other neurodegenerative disorders such as Parkinson’s disease or chronic traumatic encephalopathy are also associated with a backup of too much cell waste in the brain. “Clearance mechanisms may be very relevant to keeping these proteins at a level that isn’t disease-causing,” Nixon said.
An MRI diagnostic test for glymphatic clearance is currently in the works by Nedergaard and her colleagues. She also believes that a drug could be developed to force a cleanup if necessary, perhaps by mimicking the sleep-wake cycle.
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