The scientists tested the tissue in two ways: In a dish, researchers stressed the tissue by applying a toxin to it that destroyed a number of muscle fibers, and then watched to see if the fibers regrew.
科学家用两种方法测试培育出来的组织。研究人员在一个培养皿里给肌肉组织施放一种毒质,破坏掉一定数量的肌肉纤维,然后看纤维会不会重新生长。
The fibers did regenerate. Within 10 days after injury, the muscle regained 80% to 90% of its strength. In a separate experiment, scientists implanted the tissue into a mouse that had a 9-millimeter-wide portal implanted in its back. Within two weeks that tissue increased its strength threefold, into the range of normal muscle strength, Dr. Bursac says.
纤维真的再生了。在受伤之后10天内,肌肉恢复了80%到90%的力量。在另一项实验中,科学家将组织植入一只之前在背上植入了一个9毫米宽入口的老鼠。布尔萨奇说,两个星期之内,组织力量增加到原来的三倍,达到了正常肌肉力量的范围。
The group also replicated the work using human muscle stem cells in a dish, though that work hasn't yet been published, according to Dr. Bursac. The researchers are now working on optimizing the growth of human muscle tissue, including finding a way to get blood flow to the tissue, the best source of cells and the best growing medium for the cells.
据布尔萨奇说,团队还利用人类肌肉干细胞在一个培养皿中重复了上述实验,不过实验结果还没有发表。研究人员目前正在着手完善人类肌肉组织的培养,比如想办法让血液流入组织,找到最好的细胞源,以及为细胞寻找最好的生长介质等。
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