卡普兰的研究小组发现,一种涂有带正电聚合物的海绵状丝制材料可以培养大鼠神经元,用以替代灰质。丝制材料本身并不能让神经元产生轴突,也就是把电脉冲传递给其他神经元的突出部分。
The researchers formed the silk material into a doughnut and added collagen gel to the center. Axons grew from the ring through the gel — the white matter substitute — and sent signals to neurons across the circle.
这些研究人员将丝制材料做成一个圆圈,在其中心添加了胶原蛋白凝胶。轴突从圆圈的一边长出来,通过替代白质的凝胶,把信号发送给圆圈另一边的神经元。
They got "these neurons talking to each other," Dr. Hunziker said. "No one’s really shown that before."
亨齐克说,他们让“这些神经元互相交流。以前没人真正做到了这一点。”
By adding nutrients and growth factors, scientists kept the brainlike tissue alive in an incubator for two months, at which point they experimented on it.
通过添加营养物质和生长因子,科学家把这个类似脑的组织放在孵化器中,让其存活了两个月,然后开始在它上面做试验。
Adding a neurotoxin essentially killed the neurons, as it would in a real brain. To simulate traumatic brain injury, they dropped weights from different heights.
添加一种神经毒素基本上会把神经元杀死,就像在真正的大脑中那样。为了模拟脑外伤,他们从不同高度让重物掉到模型上。
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