医学期刊报道称,有研究专门针对影响胰岛素和营养物质的关键分子,即对雷帕霉素标靶(以下称TOR)的抑制。TOR的单一变异可以将线虫生命延长30%,而以胰岛素为标志的变异可以将寿命延长一倍。
Adding the two together might have been expected to extend longevity by 130 per cent, but the combined impact turned out to be much greater. The research may explain why it has proved so difficult to identify single genes responsible for the long lives enjoyed by humans. ‘It's quite probable that interactions between genes are critical in those fortunate enough to live very long, healthy lives,’ said Dr Kapahi. Future research is expected to use mice to see if the same effects occur in mammals.
而将两者结合可以讲人类寿命提升130%,但是两者若实际结合,其效力将不可预估。研究同样解释了判断长寿秘诀的单一基因的困难性,“这些基因之间的互相作用对于长寿、健康来说都有可能是至关重要的。”卡帕利博士说道。而未来的研究将实验于小白鼠,以验证它对哺乳动物的作用。
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