Diabetes
糖尿病
People who gain a lot of weight often stop responding to insulin. The hormone regulates the amount of glucose that cells take up from the blood; too much sugar in the blood results in type 2 diabetes. Yet grizzly bears gain 100 pounds or more each autumn and somehow avoid diabetes. A recent study found that the grizzlies' fat cells become more sensitive to insulin as they prepare for the winter, allowing the bears to keep processing and storing sugar. Scientists at biotechnology company Amgen are now testing whether tweaking the same protein that controls sensitivity in diabetic humans could have similar results.
胰岛素对肥胖人群的效果往往不佳。荷尔蒙控制细胞从血液中吸收葡萄糖的数量,而血糖过高会导致2型糖尿病。然而每年秋天灰熊都会增加100磅以上的体重却不会得糖尿病。一项近期研究发现,灰熊的脂肪细胞在准备越冬期间对胰岛素更敏感,这使得灰熊能够顺利吸收和储存糖分。人体内也有同样的蛋白质可以调整对胰岛素的敏感程度。安进公司的生物技术学家正在尝试调整这种蛋白质是否会对糖尿病人产生类似的效果。
Osteoporosis
骨质疏松症
If a human were to lie still for long periods without food, his or her bones would slowly degrade. A black bear, however, emerges from its den after winter just as strong as ever because its bone is recycled at 25 percent of normal levels during hibernation. Researchers at Colorado State University are now trying to identify the hormones that control this extreme limit on bone turnover. They aim to create a drug for people at risk for osteoporosis that similarly protects bone density.
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最新
2020-09-15
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