其中一项新研究由美国癌症协会的研究人员完成,他们发现,前列腺癌的早期诊断率从2008年的每10万名年满50岁男性540.8例下降到了2017年的416.2例,最大的下降发生在2011年至2017年间,也就是2011年10月该工作组的指南发布之后。按照研究作者们的估算,总确诊病例数从2011年的213562例减少到了2017年的180043例,相差33519例。
That difference may indicate that many men were spared needless treatment — exactly what the task force had hoped to accomplish with its guidelines. But the authors also said, “Less screening or discontinuing screening may lead to missed opportunities for detecting biologically important lesions at an early stage and preventing deaths from prostate cancer.”
该差异可能代表有许多人避免了不必要的治疗,这也是该工作组希望其指南达到的目标。但作者们表示,“减少或中止筛查可能错失时机,以致未能在早期阶段发现具有重要生物学意义的病变,从而预防因前列腺癌死亡。”
The percentage of men 50 and older who reported PSA screening in the previous 12 months dropped to 30.8 percent in 2013, from 37.8 percent in 2010.
在年满50岁的男性中,报告在过去12个月内进行过PSA筛查者的比例从2010年的37.8%下降到了2013年的30.8%。
Although the study could not prove that the drop in screening caused the drop in diagnoses, the authors said it was the most plausible explanation.
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