They added the exchange of fire took around 20 minutes.
Egyptian Interior Ministry said the attack was carried out by terrorists, affirming that one was killed and the other one was arrested.
Bombs-disposal team has defused two bombs planted nearby the church, according to the ministry.
The arrested attacker carried a bomb, 150 bullets and an automatic gun, head of Cairo Security Directorate said.
The terrorist attack has drawn regional and international condemnation.
On its twitter, the U.S. embassy in Cairo condemned the terrorist attack on Mar Mina church, saying the U.S. stands steadfastly with the people of Egypt in the face of such cowardly attacks.
"The U.S. Embassy strongly condemns today's terrorist attack on a church. We offer condolences to the families of the victims and wishes for speedy recovery for those wounded," it added.
French Ambassador in Cairo Stephane Roumtier said that Paris stands by Egypt in the face of terrorism.
Posting on his Twitter account, the French diplomat expressed his country's solidarity with the families of the victims.
Meanwhile, Secretary-General of the Organization of Islamic Cooperation (OIC) Yousef bin Ahmad al-Othaimeen expressed his sincere condolences to the families of the victims, wishing a speedy recovery for the wounded.
Othaimeen stressed OIC's solidarity with Egypt in its fight against terrorism which targets the country's security and stability.
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