Artificial sweeteners may evict good gutmicrobes

人工合成甜味剂可能会清理掉肠道内部的有益细菌

To avoid the calories in sugar, dieters oftensweeten foods and drinks with no-caloriesubstitutes, such as saccharin. But this fake sugarcould have unexpected side effects, a new studyfinds. Its authors show that a high-saccharin dietcauses changes in mice and people that could lead toobesity or type 2 diabetes. The sweetener did thatby altering microbes in the gut. Other sweeteners would likely cause similar problems, theresearchers say.

为避免糖分中过多的热量，节食者通常会在饮料和食物中添加零热量替代物将其变甜，比如说糖精。但是一项新研究发现这种"伪糖"也可能会产生意想不到的副作用。作者说明了高糖精饮食会引起老鼠和人体内部系统发生改变，通过改变肠道内的微细菌最终导致肥胖或二型糖尿病。研究者表示其他甜料也会引起类似的问题。

This research suggests "there could be unintended consequences" of using sugar substitutes,Robert Margolskee told Science News. He's a neuroscientist at the Monell Chemical SensesCenter in Philadelphia, Pa. He was not involved in the new work. "This is very interesting andscary if it really does hold for humans," he says.

宾夕法尼亚州费城莫奈尔化学感官中心的神经系统科学家Robert Margolskee告诉科学资讯使用糖的替代品会有"意外结果"产生，Robert没有参加此次研究，但他表示如果这一发现真的会给人类带来这样的结果那么真的是既有趣又恐怖。

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