The study shows for the first time the ability of platelets to regulate the expression of the oncoprotein c-MYC in cancer cells.
Elevated expression of c-MYC has been found in almost one-third of colon cancers and 42 percent of advanced pancreatic cancer, the researchers wrote, concluding that "because the interaction between platelets and cancer cells is believed to occur early ... the use of anti-platelet doses of aspirin might serve as a safe and efficacious preventive measure for patients at risk for cancer."
Consistent with epidemiological studies which show that the anti-cancer benefit of aspirin occurs at very low doses, the researchers also found that the effect on platelet function is as great at low doses as it is at the higher doses, which are sometimes used to treat inflammation, headaches or pain, suggesting that clinicians will be able to use low doses of aspirin and minimize the risk of bleeding, which is a serious concern with any antiplatelet medication.
【国际英语资讯:Low-dose aspirin found to work on blood platelets, help prevent cancer: researchers】相关文章:
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2020-09-15
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