To develop functional muscle, both the structure of the muscle tissue and how it's connected to the blood supply and nerves in the spinal cord are critical. Muscle tissue is dense and made of large muscle cells aligned in the same direction. Without the correct alignment and density, muscle cells can't generate the force they need to power a limb, for instance.
为了培育拥有机能的肌肉,肌肉组织的结构以及它与血液供应和脊髓神经的连接方式都是至关重要的。肌肉组织很紧密,由同向排列的大型肌肉细胞组成。如果排列方式和密度不合适,肌肉细胞就无法产生移动肢体等所需要的力量。
'If you're off with [the structure], then you'll be off with function,' says Nenad Bursac, a professor of biomedical engineering at Duke University.
杜克大学生物医学工程学教授内纳德·布尔萨奇(Nenad Bursac)说:“没有结构,就没有功能。”
Dr. Bursac and his team, including first author Mark Juhas, a graduate student, demonstrated for the first time in animals that they could use stem cells to create muscle tissue that repaired itself and grew stronger.
布尔萨奇和包括第一作者、研究生马克·尤哈斯(Mark Juhas)在内的团队第一次在动物身上证明,他们可以利用干细胞生成自我修复并逐渐变强的肌肉组织。
The team published the results in late March in the Proceedings of the National Academy of Sciences.
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