It is possible that pregnancy, birth and child-rearing can induce chronic stress, leading to shorter telomere length perhaps through an inflammatory pathway, said study researcher Anna Pollack, an assistant professor and environmental and reproductive epidemiologist at George Mason University. However, because the survey was conducted at a single point in time, the researchers cannot determine which came first in the women’s lives — giving birth or having shorter telomeres, Pollack said. It’s also possible that for some yet-unknown reason, women with shorter telomeres are more likely than women with longer ones to have children, Pollack said.
美国乔治梅森大学的助教、生态环境与生殖流行病学家安娜.波莱克参与了该研究,她表示:“有可能怀孕、生产和抚养孩子带来了慢性压力,并通过炎症通路缩短了端粒长度。”然而,由于调查是在某个时间点开展的,研究人员们无法确定生孩子与更短的端粒长度之间,哪一个先出现。波莱克说,有可能出于某些未知的原因,端粒更短的女性比端粒更长的女性更有可能生孩子。
More studies are needed that follow women over time and measure the length of their telomeres before, during and after pregnancy, she said.
她说,还需要进一步的追踪研究来确定女性的端粒在生孩子之前、怀孕期间和产后的长度。
It would be interesting to see how telomere length changes during pregnancy, after birth and during the child-rearing years, and how these changes compare to women who do not have children, Pollack said.
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