Perlmutter's book is propelled by a growing body of research indicating that Alzheimer's disease may really be a third type of diabetes, a discovery that highlights the close relationship between lifestyle and dementia. It also reveals a potential opening to successfully warding off debilitating brain disease through dietary changes.
Perlmutter says we need to return to the eating habits of early man, a diet generally thought to be about 75 percent fat and 5 percent carbs. The average US diet today features about 60 percent carbs and 20 percent fat. (A 20 percent share of dietary protein has remained fairly consistent, experts believe.)
Some in the nutrition and medical communities take issue with Perlmutter's premise and prescription. Several critics, while not questioning the neurological risks of a high-carb diet, have pointed out that readers may interpret his book as a green light to load up on meat and dairy instead, a choice that has its own well-documented cardiovascular health risks.
"Perlmutter uses bits and pieces of the effects of diet on cognitive outcomes — that obese people have a higher risk of cognitive impairment, for example — to construct an ultimately misleading picture of what people should eat for optimal cognitive and overall health," St. Catherine University professor emerita Julie Miller Jones, Ph.D., told the website FoodNavigator-USA.
Grain Brain does delve deeply into the neurological effects of dietary sugar. "The food we eat goes beyond its macronutrients of carbohydrates, fat and protein," Perlmutter said in a recent interview with Next Avenue. "It's information. It interacts with and instructs our genome with every mouthful, changing genetic expression."
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