“如果没有突变,这些小鼠总是会死亡,但它们存活了下来。我们看到病毒复制大幅减少,保护作用非常强。
The protein these viruses were dependent upon normally has a role in the intricate "scaffolding" which organises the inside of the body's cells, called the cytoskeleton.
这些病毒所依赖的蛋白质通常在复杂的“支架”中发挥作用,“支架”负责组织体内的细胞,被称为细胞骨架。
cytoskeleton[,saɪtə'skɛlɪtn]:n.细胞骨架,细胞支架
The findings, published in the journal Nature Microbiology, showed the genetically modified mice were healthy, despite lacking the protein for their whole lives.
这项研究结果发表在《自然微生物学》期刊上。结果显示,尽管转基因小鼠终生缺乏这种蛋白质,但它们是健康的。
人们什么时候能得到治愈?
The plan is not to produce genetically modified humans, but to find a drug which can temporarily suppress the protein, and provide protection.
科学家的目的并不是打造转基因人类,而是寻找一种能暂时抑制这种蛋白质并提供保护的药物。
"We have identified a fantastic target that all enteroviruses and rhinoviruses require and depend on. Take that away and the virus really has no chance," said Prof Carette.
“我们已经确定了所有肠病毒和鼻病毒都需要和依赖的一个极好的靶点。如果把它清除掉,病毒就没有机会兴风作浪了,”凯瑞特教授说。
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