据《科学前沿》报道,为了抵御感染,ME患者的免疫系统释放了更高水平的化合物。其中,类似免疫蛋白、干扰素γ的化合物特别多。
Interferon gamma is blamed for the extreme tiredness that follows some viral infections and has also been linked to problems with memory.
极度的疲劳感就是干扰素γ导致的,该症状紧随病毒性感染之后出现,同时与记忆损伤也有关联。
The finding may help researchers develop the first diagnostic test for ME. It also raises hope of better treatments. Drugs that lower levels of some of the immune proteins already exist.
该发现也许可以帮助研究人员进行肌痛性脑脊髓炎的首次诊断测试,同时也增加了发现更好治疗方式的希望。目前已经有一些降低免疫蛋白水平的药物。
‘This study delivers what has eluded us for so long: unequivocal evidence of immunological dysfunction in ME and diagnostic biomarkers for disease,’ said researcher Dr Ian Lipkin.
“这项研究解开了我们多年来的困惑:提供了肌痛性脑脊髓炎导致免疫功能障碍以及该病症的诊断性生物标识物的明确证据,”研究员伊恩·利普金博士说。
Lead author Dr Mady Hornig said: ‘We now have evidence confirming what millions with this disease already know, that ME isn’t psychological.’
该研究的主要作者马迪·何宁博士说:“现在我们有证据向上百万患者证明,肌痛性脑脊髓炎并不是心理疾病。”
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