先前的研究已经表明压力导致化学物质的释放,而最近密歇根大学一项发表在《普通精神病学文献》的研究发现,有遗传素质的人神经肽水平较低,患上抑郁症的风险更大。
But though research has suggested neuropeptide Y may be effective for treating psychiatric disorders, there have been problems in moving the compound into the brain. This is mainly because it is a large molecule, and has difficulty passing through the blood-brain barrier which protects the brain from potentially harmful compounds in the blood.
但是尽管研究表明,神经肽Y对治疗精神疾病有效,要将这种化合物注入脑中还很困难。这主要是因为它是一种大分子物质,要穿过保护大脑免受血液中可能有害化合物入侵的血脑屏障很困难。
However, nasal sprays can overcome this problem.
然而,鼻喷剂可以克服这一问题。
The upper part of the nose is like a back door into the brain because the nerves involved in smell provide a pathway straight into the central nervous system.
鼻腔的上部就如同进入大脑的后门,因为有关嗅觉的神经提供直接进入中枢神经系统的途径。
The new trial, which involves 15 volunteers aged 25 to 45, is designed to investigate how well the spray and neuropeptide Y work in the brain, and the effects will be compared with a placebo.
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2020-09-15
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