卡罗尔说:“对于脱靶效应的担忧也很多,比如导致目标基因组以外的基因发生突变。”换句话说,对DNA的一个区域进行编辑可能在另一区域引发问题,就像是连锁反应或多米诺骨牌效应,这点也值得担忧。
Some CRISPR critics also have argued that gene-editing may give way to eugenics and to allowing embryos to be edited with certain features in order to develop so-called designer babies.
一些基因编辑技术批评者还认为,基因编辑可能会给优生创造条件,致使人们为了孕育出所谓的“定制婴儿”而编辑胚胎的某种特征。
Though, not all experts are too concerned.
不过,并非所有专家都忧心忡忡。
The enthusiasm surrounding gene-editing in human embryos partly stems from the promise CRISPR has shown in editing away and treating devastating intractable diseases. Earlier this year, the National Academies of Sciences, Engineering, and Medicine published a report on human genome editing, addressing potential applications of gene editing, including the possible prevention or treatment of disease.
科学家们热衷于人类胚胎基因编辑研究,部分原因是基因编辑技术已经展现出消除和治疗致命性疑难杂症的前景。今年早些时候,美国国家科学院、工程院和医学院发表了一份关于人类基因组编辑的报告,讨论了基因编辑的潜在应用,比如预防或治疗疾病的可能。
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