Be aware of further self-sabotage, Ms. Goodwin said. Sloppy performance, talking back to co-workers or managers or showing up late — that’s what people do when they are unhappy at work. And it can get you fired. You may find out how much you liked, or at least needed, that job once you’re forced out.

There are times, of course, when you have to leave your job before you have another lined up, especially if it’s making you physically or emotionally ill, Ms. Rosenberg said.

A friend of mine, who asked not be named because he was still looking for a job, quit his a year ago after three and a half months. “It was a constant source of stress,” he said. “I was always in a bad mood, even on weekends.” A professional with many working years under his belt, my friend said he knew there were problems just a few weeks into the new job, but he was determined to stick it out.

“But when I went to London for a meeting, I had to double my blood-pressure medication and take a blood-pressure monitor,” he said. “That’s a sign that something’s wrong.”

He acknowledged that he thought he would find another job more quickly than was the case. In the last year, he has done consulting work and even, at times, driven a limousine. But he never regrets leaving.

“The uncertainty is uncomfortable, but it’s better than the certainty of that job,” he said.

If you’re wondering about quitting your job, Ms. Rosenberg provides a useful quiz to help with the decision on her Web site.

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